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SLEEP What is it and how does it affect us and Porphyria

Sleep—Luxury or Necessity?

TO SOME PEOPLE, sleep is a waste of time. Preferring a very busy daily schedule of business and social engagements, they only surrender to sleep when extremely tired. In contrast, others, enduring night after night of tossing and turning until the early hours of the morning, would give anything for a good night’s sleep.
Why do some find it so hard to sleep, while others are desperate to stay awake? Should we view sleep as a luxury or a necessity? To answer these questions, we need to understand what is going on while we are asleep.
The Mysteries of Falling Asleep
Exactly what makes a person lose consciousness and fall asleep remains a mystery. Researchers, however, have established that sleep is a complex process regulated by the brain and that it obeys a 24-hour biological clock.
As we get older, our sleeping habits change. A newborn sleeps for frequent short periods that total about 18 hours a day. According to sleep specialists, although some adults appear to need only three hours of sleep a day, others need up to ten hours.

Recent research has shown that variations in our biological clock also explain why some teenagers struggle to get out of bed in the morning. The biological clock seems to shift forward during puberty, making youngsters want to go to sleep later and wake up later. This sleep delay is common and tends to disappear in the mid-to-late teens.
Our biological clock is regulated by chemical substances, many of which have already been identified. One of them is melatonin, a hormone thought to trigger sleepiness. Melatonin is produced in the brain, and some scientists believe that it is responsible for the slowdown of the body’s metabolism that occurs prior to falling asleep. As melatonin is released, body temperature and blood flow to the brain are reduced, and our muscles gradually lose their tone and become flaccid. What happens next as the person descends into the mysterious world of sleep?
‘Nature’s Chief Nourisher’
Approximately two hours after we fall asleep, our eyes begin to quiver quickly back and forth. The observation of this phenomenon led scientists to divide sleep into two basic phases: REM (rapid eye movement) sleep and non-REM sleep. Non-REM sleep can be subdivided into four stages of progressively deeper sleep. During a healthy night’s sleep, REM sleep occurs several times, alternating with non-REM sleep.
Most dreaming occurs during REM sleep. The body also experiences maximum muscle relaxation, which allows the sleeper to wake up feeling physically refreshed. In addition, some researchers believe that newly acquired information is consolidated as part of our long-term memory during this sleep stage.
During deep sleep (non-REM sleep stages 3 and 4), our blood pressure and heart rate reach lower ranges, providing rest for the ...

... circulatory system and helping to ward off cardiovascular disease. In addition, the production of growth hormone peaks during non-REM sleep, with some teenagers producing as much as 50 times more growth hormone at night than during the day.
Sleep also seems to affect our appetite. Scientists have discovered that sleep really is, to quote Shakespeare, “chief nourisher in life’s feast.” Our brain interprets a lack of sleep as a lack of food. While we sleep, our organism secretes leptin, the hormone that normally lets our body know that we have eaten enough. When we stay awake longer than we should, our body produces less leptin, and we feel a craving for more carbohydrates. So sleep deprivation can lead to increased carbohydrate consumption, which in turn can lead to obesity.—See the box “An Afternoon Nap,” on page 6.
Page 6
Vital for Health
But that is not all. Sleep makes it easier for our body to metabolize free radicals—molecules that are said to affect the aging of cells and even cause cancer. In a recent study carried out by the University of Chicago, 11 healthy young men were allowed only four hours of sleep a day for six days. At the end of this period, their body cells were performing like those of 60-year-olds, and their blood insulin level was comparable with that of a diabetes sufferer! Sleep deprivation even affects the production of white blood cells and the hormone cortisol, making a person more prone to infections and circulatory diseases.
Without a doubt, sleep is vital for a healthy body and mind. In the opinion of researcher William Dement, founder of the first sleep study center, at Stanford University, U.S.A., “sleep seems to be the most important indicator of how long you’ll live.” Deborah Suchecki, researcher at a sleep study center in São Paulo, Brazil, comments: “If people knew what is going on in a sleep-deprived body, they would think twice about concluding that sleep is a waste of time or just for the lazy.”—See the box above.
But is all sleep restorative? Why do some people sleep the whole night and still feel unrefreshed? The next article will help you identify some of the principal sleep disorders and will explain how you can get quality sleep.

 Sudden mood swings
 Loss of short-term memory
 Loss of capacity to create, plan, and carry out activities
 Loss of concentration
 Premature aging
 Increased risk of infections, diabetes, cardiovascular diseases, and gastrointestinal disease
 Chronic memory loss

Have you ever felt an uncontrollable drowsiness after lunch? This is not necessarily a sign that you are suffering from sleep deprivation. It is normal to feel sleepy in the early afternoon because of a natural drop in body temperature. In addition, scientists have recently discovered a protein called hypocretin, or orexin, that is produced in the brain and helps keep us awake. What is the connection between hypocretin and food?
When we eat, the body produces leptin to give us the impression that we are full. But leptin inhibits the production of hypocretin. In other words, the more leptin there is in the brain, the less hypocretin and the greater the feeling of drowsiness. Perhaps that is why in some countries people take a siesta—a break in the workday that allows people to sleep a little after lunch.

"Remember....Research is the key to your cure!"


  1. useful information on topics that plenty are interested on for this wonderful post.Admiring the time and effort you put into your b!.. Sleep disorders

  2. An adjustment in eating regimen and way of life with subsequent decrease in corpulence can likewise particularly lessen the seriousness of indications. sleep with valium


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                  Happy Winter Season!